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Potent alkaline phosphate inhibitor. Mimics the action of orthovanadate in the potentiation of fluorouracil antiproliferative activity. Cell permeable.
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HIV-1 inhibitor-8 is an orally active, low-toxicity non-nucleoside reverse transcriptase inhibitor used in research to evaluate antiviral activity against HIV-1 strains.
Orally active non-nucleoside reverse transcriptase inhibitor for research use.
Potent antiviral activity (EC50 = 4.44-54.5 nM) against various HIV-1 strains.
Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) was identified as a metastatic driver CEACAM5 overproduction enriched for an epithelial gene expression pattern and facilitated tumor outgrowth at metastatic sites Tissues from patients with metastatic breast cancer confirmed elevated levels of CEACAM5 in lung metastases relative to breast tumors and an inverse correlation between CEACAM5 and the mesenchymal marker vimentin was demonstrated
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A cell-permeable inhibitor that binds ERK2 near its docking domain (KD = 5 µM); blocks ERK-specific phosphorylation of Rsk-1 and TCF/Elk-1 but does not affect ERK1/2 phosphorylation by MEK1/2; completely prevents proliferation of several cancer cell lines
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h/m P53-sh-RFP/Luc shRNA lentiviral vector expressing RFP/Luc with selection for studies in Human/Mouse Each vial provides a nominal titer of 2x10E6 transducing units TU Validated human P53 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human tumor suppressor protein p53 (P53/TP53) The shRNA has been validated to meet or exceed 70% P53 knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
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The A29L protein from Monkeypox binds to cell surface heparin to promote fusion of viral membrane with host plasma membrane it is a potential target for developing diagnosis and vaccine
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More